Routine immunisation programmes

Age due Vaccines that protect against Vaccine given Trade name Usual site [note 1]  
8 weeks old Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B DTaP/IPV/Hib/HepB (6 in 1 vaccine) Infanrix hexa or Vaxelis Thigh  
  Meningococcal group B (MenB) MenB Bexsero Thigh  
  Rotavirus gastroenteritis Rotavirus Rotarix [note 2] By mouth  
12 weeks old Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B   DTaP/IPV/Hib/HepB (6 in 1 vaccine) Infanrix hexa or Vaxelis Thigh
  MenB MenB Bexsero Thigh  
  Rotavirus Rotavirus Rotarix [note 2] By mouth  
16 weeks old Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B DTaP/IPV/Hib/HepB (6 in 1 vaccine) Infanrix hexa or Vaxelis Thigh  
  Pneumococcal (13 serotypes)
• if received pneumococcal at 12 weeks give Men B		   PCV Prevenar 13 Thigh
One year old (on or after the child’s first birthday) Born before 1 July 2024 Born on or after 1 July 2024      
  Pneumococcal Pneumococcal PCV Prevenar 13 Upper arm or thigh
  Measles, mumps, rubella Measles, mumps, rubella MMR MMRvaxPro or Priorix  
  MenB MenB MenB Bexsero  
  Hib/MenC (if Hib/MenC exhausted give DTaP/Hib/IPV/HepB)   Hib/MenC Menitorix  
18 months old Born before 1 July 2024 Born on or after 1 July 2024      
  No appointment DTaP/IPV/Hib/HepB DTaP/IPV/Hib/HepB Infanrix hexa or Vaxelis Upper arm or thigh
    Measles, mumps, rubella MMR MMRvaxPro or Priorix  
3 years 4 months old or soon after Born before 1 July 2024 Born on or after 1 July 2024      
  Diphtheria, tetanus, pertussis and polio Diphtheria, tetanus, pertussis and polio dTaP/IPV REPEVAX Upper arm or thigh
  Measles, mumps, rubella   MMR MMRvaxPro or Priorix  
Age due Vaccines that protect against Vaccine given Trade name Usual site [footnote 1]
Boys and girls aged 12 to 13 years Cancers and genital warts caused by specific human papillomavirus (HPV) types HPV Gardasil 9 Upper arm
14 years old (school Year 9) Tetanus, diphtheria and polio Td/IPV REVAXIS Upper arm
  Meningococcal groups A, C, W and Y MenACWY MenQuadfi Upper arm
Eligible paediatric age group
See annual flu letter
(each year from September)		 Influenza LAIV (Live attenuated influenza vaccine)
• If LAIV is contraindicated or otherwise unsuitable use inactivated flu vaccine (check Green Book chapter 19 for details)		 Fluenz (contains porcine gelatine) Both nostrils
65 years old Pneumococcal (23 serotypes) Pneumococcal polysaccharide vaccine (PPV23) Pneumovax 23 Upper arm
65 years of age and older Influenza (each year from September) Inactivated influenza vaccine Multiple Upper arm
65 from September 2023 ) Shingles Shingles vaccine Shingrix Upper arm
70 to 79 years of age (plus eligible age groups and severely immunosuppressed) Shingles Shingles vaccine Zostavax 
(or Shingrix if Zostavax contraindicated)		 Upper arm
75 years old Respiratory syncytial virus (RSV) RSV vaccine Abrysvo Upper arm

Notes

  1. Intramuscular injection into deltoid muscle in upper arm or anterolateral aspect of the thigh.
  2. Rotavirus vaccine should only be given after checking for SCID screening result.

Selective immunisation programmes

Target group Age and schedule Disease Vaccines required  
Babies born to women with hepatitis B infection  [note 1], [note 2 At birth, 4 weeks
if born before 01 July 2024 give additional dose at 12 months old [note 1]		 Hepatitis B Hepatitis B (Engerix B/HBvaxPRO)  
Infants in areas of the country with tuberculosis (TB) incidence >= 40/100,000 Around 28 days old [note 4] Tuberculosis BCG  
Infants with a parent or grandparent born in a high incidence country [note3] Around 28 days old [note 4] Tuberculosis BCG  
Children in a clinical risk group Age under 2 years
• if first ever flu vaccine give second dose at 4 weeks		 Influenza inactivated flu vaccine  
  Age under 2 years
• if first ever flu vaccine give second dose at 4 weeks		 Influenza LAIV or inactivated flu vaccine if contraindicated to LAIV   
  Age 9 to 17 years
• one dose required each flu season		 Influenza LAIV or inactivated flu vaccine if contraindicated to LAIV   
Pregnant women At any stage of pregnancy during flu season Influenza Inactivated flu vaccine  
  From 16 weeks gestation [note 5] Pertussis Tdap (ADACEL)  
  From 28 weeks gestation RSV RSV vaccine (Abrysvo)  

Notes

  1. Take blood for HBsAg on or after 12 months to exclude infection. For children born on or after 1 July 2024, test anytime between 12 and 18 months.
  2. In addition hexavalent vaccine (Infanrix hexa or Vaxelis) is given at 8, 12 and 16 weeks and, for children born on or after 1 July 2024, also at 18 months.
  3. Where the annual incidence of TB is 40 per 100,000 or higher – see TB incidence by country.
  4. Check SCID screening outcome before giving BCG.
  5. Ideally before 32 weeks gestation but may still be given after 32 weeks.

Additional vaccines for individuals with underlying medical conditions

Medical condition Diseases protected against Vaccines required [note 1]
Asplenia or splenic dysfunction 
(this also includes individuals with coeliac disease who are diagnosed with splenic dysfunction and all haemoglobinopathies including homozygous sickle cell disease)		 Meningococcal groups A, B, C, W and Y MenACWY
MenB
  Pneumococcal PCV13 (up to 10 years of age) [note 2]
PPV23 (from 2 years of age)
  Influenza Annual flu vaccine
Cochlear implants Pneumococcal PCV13 (up to 10 years of age) [note 2]
PPV23 (from 2 years of age)
Chronic respiratory and heart conditions (such as severe asthma, chronic pulmonary disease, and heart failure) Pneumococcal PCV13 (up to 10 years of age)[note 2]
PPV23 (from 2 years of age)
  Influenza Annual flu vaccine
Chronic neurological conditions Pneumococcal (only if the individual is also at increased risk of aspiration) PCV13 (up to 10 years of age) [note 2]
PPV23 (from 2 years of age)
  Influenza Annual flu vaccine
Diabetes Pneumococcal PCV13 (up to 10 years of age) [note 2]
PPV23 (from 2 years of age)
  Influenza Annual flu vaccine
Chronic kidney disease (CKD) (including haemodialysis) Pneumococcal (stage 4 and 5 CKD) PCV13 (up to 10 years of age) [note 2]
PPV23 (from 2 years of age)
  Influenza (stage 3, 4 and 5 CKD) Annual flu vaccine
  Hepatitis B (stage 4 and 5 CKD) Hepatitis B
Chronic liver conditions Pneumococcal PCV13 (up to 10 years of age) [note 2]
PPV23 (from 2 years of age)
  Influenza Annual flu vaccine
  Hepatitis A Hepatitis A
  Hepatitis B Hepatitis B
Haemophilia Hepatitis A Hepatitis A
  Hepatitis B Hepatitis B
Immunosuppression due to disease or treatment [note 4] Pneumococcal PCV13 (up to 10 years of age) [note 2] ,[note 3]
PPV23 (from 2 years of age)
  Shingles vaccine Shingrix – over 50 years of age [note 5]
  Influenza Annual flu vaccine
Complement disorders (including those receiving complement inhibitor therapy) Meningococcal groups A, B, C, W and Y MenACWY
MenB
  Pneumococcal PCV13 (up to 10 years of age) [note 2]
PPV23 (from 2 years of age
  Influenza Annual flu vaccine

Notes

  1. Check relevant chapter of the Green Book for specific schedule.
  2. If aged 2 years to under 10 years of age and unimmunised or partially immunised against pneumococcal infection, give one PCV13 dose.
  3. To any age in severely immunosuppressed.
  4. Consider annual influenza vaccination for household members and those who care for people with these conditions.
  5. Check Green Book Shingles Chapter 28a www.gov.uk/government/publications/ shingles-herpes-zoster-the-green-book-chapter-28a

Back to top

Published: Jul 1, 2025